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This uptake of PAH is an example of tertiary active transport because the basolateral Na/dicarboxylate cotransporter NaDC3—in a process of secondary active transport —elevates α-KG in the cell, thereby creating the outward α-KG gradient

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Differential gene expression analysis was performed on the different subgroups with a base mean value of expression greater than 1, log2 fold change greater than 0.6 and an adjusted p -value less than 0.1 using the DESeq2 pipeline 124